Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis This gene encodes a protein

This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus

Following type I IFN binding to cell surface receptors| Jak kinases (TYK2 and JAK1) are activated| leading to tyrosine phosphorylation of STAT1 and STAT2

Osteoporotic bones are more at risk of fracture

Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK

SYK and LAT via its SH2 domain

Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis This gene encodes a proteinMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.