PIGR Polyclonal Antibody, 50ul Gloves Mutations in CBX2 are also

Mutations in CBX2 are also associated with gonadal dysgenesis in humans

consistent with the observation that it binds directly to pre-mRNA

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes| platelet dense granules| and lysosomes

The protein can bind to the HIV-1 TAR mRNA

This protein also interacts with and is acetylated by MCM3AP

PIGR Polyclonal Antibody, 50ul Gloves Mutations in CBX2 are alsoThis gene is a member of the immunoglobulin superfamily. The encoded poly Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.