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p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction The gene product is required

SKU: 32344931569

4.4
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p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction The gene product is requiredTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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Description

The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells

Contains 1 PLA2c domain

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone

Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase| this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis

p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction The gene product is requiredTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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