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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression This gene encodes a cysteine-rich

SKU: 31880263155

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression This gene encodes a cysteine-richThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver

these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues)

NK2 homeobox is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman'

which then activates a specific MAPK

Among its related pathways are Endocytosis and Notch Signaling Pathways

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression This gene encodes a cysteine-richThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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