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PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis and over-expression of this gene

SKU: 31670119647

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SEK162.00 SEK194.00

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PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis and over-expression of this geneThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

and over-expression of this gene is implicated in tumor growth and metastasis

Receptor-type tyrosine-protein phosphatase eta encoded by PTPRJ is a member of the protein tyrosine phosphatase (PTP) family

This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination

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PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis and over-expression of this geneThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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