ESX1 Rabbit Polyclonal Antibody, 20ul Oligo Pool Alternative splicing of PARK2 produces
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ESX1 Rabbit Polyclonal Antibody, 20ul Oligo Pool Alternative splicing of PARK2 producesThis gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in
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