ERH Rabbit Polyclonal Antibody, 50ul Cell Culture Plates The SMN complex is localized

The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing

It consists of five identical glycoprotein subunits| each with EGF-like and calcium-binding (thrombospondin-like) domains

results in a greater abundance of the unspliced form of the transcript than the spliced form

Participates in chain elongation of fatty acids

Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants

ERH Rabbit Polyclonal Antibody, 50ul Cell Culture Plates The SMN complex is localized