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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ Protein Red localizes to discrete

SKU: 2999764662

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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ Protein Red localizes to discreteThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Protein Red localizes to discrete dots within the nucleus

The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit

An important paralog of this gene is JMJD7-PLA2G4B

displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID: 15866175)

nuclear DNA-binding protein regulates transcription

Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ Protein Red localizes to discreteThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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