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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every time

SKU: 2992719349

4.1
SEK185.00 SEK217.00

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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every timeTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

high-quality results every time

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins

A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient

Alternative splicing of DYRK1A generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region

this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development

p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every timeTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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