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CT452 Rabbit Polyclonal Antibody, 50ul Filtration Alternative splicing of this gene

SKU: 29799622326

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CT452 Rabbit Polyclonal Antibody, 50ul Filtration Alternative splicing of this geneThis gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer testis (CT) family of antigens and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers.

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Description

Alternative splicing of this gene generates four transcript variants

It is expressed by hepatocytes

also known as PUMAG or Puma-g

HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity

Two alternatively spliced transcript variants for this gene have been described

CT452 Rabbit Polyclonal Antibody, 50ul Filtration Alternative splicing of this geneThis gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer testis (CT) family of antigens and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers.

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