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DPYD Polyclonal Antibody, 20ul Multiplex Immunoassays Multiple alternatively spliced transcript variants

SKU: 2962103161

4.6
SEK97.20 SEK123.20

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DPYD Polyclonal Antibody, 20ul Multiplex Immunoassays Multiple alternatively spliced transcript variantsDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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Description

Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported

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DPYD Polyclonal Antibody, 20ul Multiplex Immunoassays Multiple alternatively spliced transcript variantsDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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