CD59 Polyclonal Antibody, 50ul[BT-AP01766] Organelle Studies Component of the SCF(FBXO11) complex

Component of the SCF(FBXO11) complex containing FBXO11

Several protein-coding and non-protein coding transcript variants have been found for this gene

Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene

The protein encoded by MCM3AP (minichromosome maintenance complex component 3 associated protein) is a MCM3 binding protein

This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses| including proliferation| differentiation| and phagocytosis

CD59 Polyclonal Antibody, 50ul[BT-AP01766] Organelle Studies Component of the SCF(FBXO11) complexIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated,