Rad17(Phospho-Ser635) Rabbit Polyclonal Antibody, 100ul Vacuum Filter also named activator 1

also named activator 1

This protein is part of the COPII coat complex

and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins

which act as heat shock protein 70 cochaperones

belongs to the protein kinase superfamily

Rad17(Phospho-Ser635) Rabbit Polyclonal Antibody, 100ul Vacuum Filter also named activator 1The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17 a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC) and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This