FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 50ul Cell Function Analysis The protein lacks critical active

The protein lacks critical active site residues and thus is suggested to be proteolytically inactive

as well as fetal brain and liver and hematopoietic cell lines

nuclear 1) gene

50mL change 15mL adapter

as well as increased surface expression of cell activation markers

FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 50ul Cell Function Analysis The protein lacks critical activedisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.