ADNP Polyclonal Antibody, 100ul Vortex Mixer Disruption of the TGF-beta/SMAD pathway

Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers

Nine mammalian isotypes have been identified

regulates cell differentiation in multiple tissues

The encoded kinase (casein kinase 1 gamma 1) plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

Mutations in this gene have been associated with Charcot-Marie-Tooth disease

ADNP Polyclonal Antibody, 100ul Vortex Mixer Disruption of the TGF-beta/SMAD pathwayVasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a