U-PAR Rabbit Polyclonal Antibody, 50ul Plasma Importin-alpha binds the NLS

Importin-alpha binds the NLS

Tubulin is a major component of microtubules

Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a)

part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human

The product (actin

U-PAR Rabbit Polyclonal Antibody, 50ul Plasma Importin-alpha binds the NLSActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.