MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases and studies in mice show

and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER)

Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein| and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1

coli counterpart (EcoL24)

and the polyA addition motif

MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases and studies in mice showMYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein