Rat Topoisomerase 2, TOP2 ELISA Kit, 96T Sealing Film The encoded protein is thought

The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis

The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21

DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18

It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally

The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone

Rat Topoisomerase 2, TOP2 ELISA Kit, 96T Sealing Film The encoded protein is thoughtKey decatenating enzyme that alters DNA topology by binding to two double stranded DNA molecules, generating a double stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (By similarity). May play a role in regulating the period length of ARNTL BMAL1 transcriptional oscillation (By similarity).