RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets and RNA processing and transport
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RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets and RNA processing and transportA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in
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