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RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets and RNA processing and transport

SKU: 28034417540

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RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets and RNA processing and transportA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in

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Description

and RNA processing and transport

The product of NFATC3

The beta subunit is a non-DNA binding regulatory subunit

It may play a role in tumorigenesis and metastasis

Two alternatively spliced transcript variants encoding distinct proteins have been described

RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets and RNA processing and transportA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in

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