ADR2 Rabbit Polyclonal Antibody, 100ul Vacuum Filter thus targeting specific proteins for

thus targeting specific proteins for lysosomal degradation

An important paralog of PLK5 is PLK4

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

Cathepsin L1 encoded by CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism

A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon

ADR2 Rabbit Polyclonal Antibody, 100ul Vacuum Filter thus targeting specific proteins forThe adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003