BNIP-3 Polyclonal Antibody, 100ul[BT-AP00949] Immune Cell Analysis As a component of the

As a component of the inflammasome

These proteins contain conserved cysteine residues at fixed positions| and are distantly related to MIP-1alpha| a member of the CC-chemokine family

Acting as a GTPase activating protein (GAP)

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The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination

BNIP-3 Polyclonal Antibody, 100ul[BT-AP00949] Immune Cell Analysis As a component of theBNIP3 is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The BCL2 interacting protein 3 interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.