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MAD2 Polyclonal Antibody, 50ul Low retention tips which suggests an essential role

SKU: 27088655546

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MAD2 Polyclonal Antibody, 50ul Low retention tips which suggests an essential roleMAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

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Description

which suggests an essential role of this gene in the immune response to antigenic stimuli

The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein

and chondrocyte terminal differentiation

ThAKAP8 encodes a nuclear A-kinase anchor protein (A-kinase anchoring protein 8) that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin

PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways

MAD2 Polyclonal Antibody, 50ul Low retention tips which suggests an essential roleMAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

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