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p53 Polyclonal Antibody, 100ul[BT-AP06819] Capsule Filter Alternative splicing results in multiple

SKU: 27059173368

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p53 Polyclonal Antibody, 100ul[BT-AP06819] Capsule Filter Alternative splicing results in multipleTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternative splicing results in multiple variants

This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight)

Catalytic activity:Nucleoside 3'

Mutations in this gene are associated with Warburg micro syndrome type 3

Only expressed during spermiogenesis

p53 Polyclonal Antibody, 100ul[BT-AP06819] Capsule Filter Alternative splicing results in multipleTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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