CD56 Polyclonal Antibody, 20ul[BT-AP01761] Lentiviral Packaging Expansion of a polyalanine tract

Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy

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CD56 Polyclonal Antibody, 20ul[BT-AP01761] Lentiviral Packaging Expansion of a polyalanine tractThe checkpoint kinase 1 encoded by CHEK1 belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required