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V-ATPase B1 Polyclonal Antibody, 100ul Lentiviral Packaging and appears to determine the

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V-ATPase B1 Polyclonal Antibody, 100ul Lentiviral Packaging and appears to determine theATP6V1B1 encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain

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Description

and appears to determine the specificity of the protein's homophilic cell adhesion activity

The association with SMAD4 is important for the translocation

The protein is made as a precursor that is autocatalytically cleaved| the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology

V-ATPase B1 Polyclonal Antibody, 100ul Lentiviral Packaging and appears to determine theATP6V1B1 encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain

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