LIMK-2 Polyclonal Antibody, 50ul[BT-AP05022] Serum also designated High-glucose-regulated protein 8

also designated High-glucose-regulated protein 8

Belongs to the PIP family

The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions| where they appear to provide protective functions

Transmembrane topology has been established for two family members (FXYD1 and FXYD2)

The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex

LIMK-2 Polyclonal Antibody, 50ul[BT-AP05022] Serum also designated High-glucose-regulated protein 8There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase