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EDG-4 Polyclonal Antibody, 20ul[BT-AP02830] Liquid Handling &Storage Mutations affecting this gene are

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EDG-4 Polyclonal Antibody, 20ul[BT-AP02830] Liquid Handling &Storage Mutations affecting this gene areS1PR3 encodes a member of the EDG family of receptors, which are G protein coupled receptors. This protein has been identified as a functional receptor for sphingosine 1 phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

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Description

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways

The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region

Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes

Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade

EDG-4 Polyclonal Antibody, 20ul[BT-AP02830] Liquid Handling &Storage Mutations affecting this gene areS1PR3 encodes a member of the EDG family of receptors, which are G protein coupled receptors. This protein has been identified as a functional receptor for sphingosine 1 phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

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