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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a protein

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a proteinLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

This gene encodes a protein containing an alpha/beta hydrolase fold| which is a catalytic domain found in a very wide range of enzymes

The genomic region is also rich in Alu repetitive sequences

Secretin and its receptor are suggested to be involved in pancreatic cancer and autism

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

Belongs to the vinculin/alpha-catenin family

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This gene encodes a proteinLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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