PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification The encoded protein plays a

The encoded protein plays a role in many cellular processes including cell cycle progression

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway

2003 [PubMed 14508493])

This gene encodes a subunit of a tRNA-specific adenosine deaminase

Mutations in this gene have been associated with autosomal dominant high myopia (MYP24)

PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification The encoded protein plays aThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in