IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter Multiple phosphorylation sites have been

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

Pseudogenes corresponding to this gene are found on chromosomes 3p

also known as AGBL2 (ATP/GTP binding protein-like 2)

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

ERI1 binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter Multiple phosphorylation sites have beenThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell