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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis RBM5 is a candidate tumor

SKU: 26220798164

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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis RBM5 is a candidate tumorThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

RBM5 is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex

Each isoenzyme is a homodimer composed of 2 alpha

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis RBM5 is a candidate tumorThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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