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JMJD2B Polyclonal Antibody, 100ul Custom Peptide Synthesis This protein kinase is calcium-independent

SKU: 25798717883

4.9
USD123.75 USD167.75

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JMJD2B Polyclonal Antibody, 100ul Custom Peptide Synthesis This protein kinase is calcium-independentHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

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Description

This protein kinase is calcium-independent and phospholipid-dependent

also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3

and susceptibility to virus and parasite

GPS1 is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells

Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS)

JMJD2B Polyclonal Antibody, 100ul Custom Peptide Synthesis This protein kinase is calcium-independentHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

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