Beclin-1 Polyclonal Antibody, 100ul[BT-AP00883] Enzyme-Linked Immunosorbent Assay (ELISA) survival and intracellular trafficking

survival and intracellular trafficking

This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases

p34) with TFE3

an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function

and quenchers

Beclin-1 Polyclonal Antibody, 100ul[BT-AP00883] Enzyme-Linked Immunosorbent Assay (ELISA) survival and intracellular traffickingBECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.