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Rat Major Prion Protein, PRNP ELISA Kit, 96T Biomatrix and over-expression of this gene

SKU: 24737673253

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Rat Major Prion Protein, PRNP ELISA Kit, 96T Biomatrix and over-expression of this geneIts primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan

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Description

and over-expression of this gene is implicated in tumor growth and metastasis

while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21

The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation

Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2

Activates procollagenase

Rat Major Prion Protein, PRNP ELISA Kit, 96T Biomatrix and over-expression of this geneIts primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan

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