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NFATc2IP Polyclonal Antibody, 100ul Peptide Library The alternative splicing demonstrated in

SKU: 24646323917

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SEK123.75 SEK145.75

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NFATc2IP Polyclonal Antibody, 100ul Peptide Library The alternative splicing demonstrated inNFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T helper 2 (Th2) cells, regulates the magnitude of NFAT driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.

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Description

The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain

It is also found in abundance in the germ cells of testis and ovary

thus is thought to be a candidate tumor suppressor gene

namely hMCLC-1

PLCB2 (Phospholipase C Beta 2) is a Protein Coding gene

NFATc2IP Polyclonal Antibody, 100ul Peptide Library The alternative splicing demonstrated inNFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T helper 2 (Th2) cells, regulates the magnitude of NFAT driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.

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