GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation The alpha and alpha' chains

The alpha and alpha' chains contain the catalytic site

Mutations and deletions in NKX2-1 are associated with benign hereditary chorea

Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites

An important paralog of this gene is CSNK1G2

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation The alpha and alpha' chainsThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.