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PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers and is a key regulator

SKU: 24128307322

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PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers and is a key regulatorPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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Description

and is a key regulator of xenobiotic and endobiotic metabolism

This gene is expressed at high levels in primary neutrophils and primary monocytes

peripheral blood leukocyte

and inactivated by two groups of GTPase-activating proteins (GAPs)

mutations in this gene can cause the autosomal recessive form of Robinow syndrome

PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers and is a key regulatorPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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