SP6 Polyclonal Antibody, 100ul Enzymes This chain is unusual in

This chain is unusual in that

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane

associates with endocytic vesicles

The protein encoded by this gene plays a crucial role in B-cell development

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

SP6 Polyclonal Antibody, 100ul Enzymes This chain is unusual inSP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes (Scohy et al., 2000