HDAC1 (Acetyl Lys220) Rabbit Polyclonal Antibody, 50ul Filtration The protein encoded by ARNTL

The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK

Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes

This gene| also called CES5| is predominantly expressed in peripheral tissues| including brain| kidney| lung and testis

and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex

This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor

HDAC1 (Acetyl Lys220) Rabbit Polyclonal Antibody, 50ul Filtration The protein encoded by ARNTLCatalytic activity: Hydrolysis of an N(6) acetyl lysine residue of a histone to yield a deacetylated histone. Responsible for the deacetylation of lysine residues on the N terminal part of the core histones (H2A H2B H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation cell cycle progression and developmental events. Histone deacetylases act via the formation of large