IKZF5 Rabbit Polyclonal Antibody, 20ul Mechanical Pipette The gene product also affects

The gene product also affects fibroblast growth factor signaling

and thereby plays an important role in axon growth and axon guidance (By similarity)

Alternate splicing of this gene results in three transcript variants encoding different isoforms

Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner

This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts

IKZF5 Rabbit Polyclonal Antibody, 20ul Mechanical Pipette The gene product also affectsMembers of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors which includes Pegasus are expressed in lymphocytes and are implicated in the control of lymphoid development.