Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment PubMed: 18305108)

PubMed: 18305108)

The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities

Multiple transcript variants encoding several different isoforms have been found for APP

including proliferation

GPR35 (G protein-coupled receptor 35) is a 309 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family

Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment PubMed: 18305108)This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.