Bub1 Polyclonal Antibody, 100ul[BT-AP01008] Inoculating Loops/Needles Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants of CDC25C have been described

acatalasemia is the only disease known to be caused by CAT

A related pseudogene has been identified on chromosome 17

an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma

PTM:Covalently linked to a small RNA of about 20 nucleotides

Bub1 Polyclonal Antibody, 100ul[BT-AP01008] Inoculating Loops/Needles Multiple alternatively spliced transcript variantsBUB1 (BUB1 mitotic checkpoint serine threonine kinase) encodes a serine threonine protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex cyclosome. This protein may also function in the DNA damage response. Mutations in BUB1