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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification indicating a potential role for

SKU: 22639030587

4.3
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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification indicating a potential role forCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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Description

indicating a potential role for this protein in DNA repair

RNA polymerase III subunit A encoded by POLR3A is the catalytic component of RNA polymerase III

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Expressed specifically in the hippocampus and Purkinje cells of the brain

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification indicating a potential role forCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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