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Cleaved-Ephrin-A4 (S170) Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator A pseudogene of this gene

SKU: 22537425255

4.2
PLN97.20 PLN137.20

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Cleaved-Ephrin-A4 (S170) Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator A pseudogene of this geneMay play a role in the interaction between activated B lymphocytes and dendritic cells in tonsils. Belongs to the ephrin family. tissue specificity: Expressed in the adult spleen lymph node prostate ovary small intestine and colon and in fetal heart lung liver and kidney. Also detected in hematopoietic cell lines.

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Description

A pseudogene of this gene is found on chromosome 8

MIM 103880)| makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham| 1995

Members of the VCX/Y family share a high degree of sequence identity| with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

An important paralog of this gene is IFITM1

Cleaved-Ephrin-A4 (S170) Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator A pseudogene of this geneMay play a role in the interaction between activated B lymphocytes and dendritic cells in tonsils. Belongs to the ephrin family. tissue specificity: Expressed in the adult spleen lymph node prostate ovary small intestine and colon and in fetal heart lung liver and kidney. Also detected in hematopoietic cell lines.

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