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Akt1 Polyclonal Antibody, 100ul[BT-AP00348] Contamination Detection & Removal This gene encodes a DEAD

SKU: 22237091599

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SEK123.75 SEK165.75

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Akt1 Polyclonal Antibody, 100ul[BT-AP00348] Contamination Detection & Removal This gene encodes a DEADThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

This gene encodes a DEAD box protein

Activity of this receptor has also been linked to carcinogenesis

The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14

this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH)

Mutations in this gene cause early infantile epileptic encephalopathy 25

Akt1 Polyclonal Antibody, 100ul[BT-AP00348] Contamination Detection & Removal This gene encodes a DEADThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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