TRI11 Rabbit Polyclonal Antibody, 100ul Buffers & Solutions Regulator of calcineurin 1 encoded

Regulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways

Mutations in this gene have been identified in aggressive neuroblastomas

Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase

Mutations in PPP2R1B have been associated with some lung and colon cancers

MRPS18C encodes a 28S subunit protein that belongs to the ribosomal protein S18P family

TRI11 Rabbit Polyclonal Antibody, 100ul Buffers & Solutions Regulator of calcineurin 1 encodedThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.