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MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage Reduced expression and rearrangement of

SKU: 22176335838

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MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage Reduced expression and rearrangement ofThis gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS

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Description

Reduced expression and rearrangement of this gene have been detected in various cancers

|disease:A chromosomal aberration involving BCL6 may be a cause of lymphoma

some of which do not encode a protein with a predicted signal peptide

The high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin

Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele

MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage Reduced expression and rearrangement ofThis gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS

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