FAN Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Mutations in THRB are known

Mutations in THRB are known to be a cause of generalized thyroid hormone resistance (GTHR)

a cDNA for arrestin beta 2 was isolated from thyroid gland

This gene has no introns

by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases

This gene encodes a pentaspan transmembrane glycoprotein

FAN Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Mutations in THRB are knownThis gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.