PEA-15(Phospho Ser104) Polyclonal Antibody, 20ul NGS Oligos Two alternatively spliced variants have

Two alternatively spliced variants have been described

tissue specificity:Expression restricted to nervous system and testis

miscellaneous:L-leucine transport activity inhibited by small zwitterionic amino acids (i

MAP4K1 is a Protein Coding gene

Mutations in this gene have been associated with primary pulmonary hypertension| both familial and fenfluramine-associated| and with pulmonary venoocclusive disea

PEA-15(Phospho Ser104) Polyclonal Antibody, 20ul NGS Oligos Two alternatively spliced variants haveThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.