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Akt2 Monoclonal Antibody, 100ul Recombinant Ab Production Acts as a GTPase activitor

SKU: 21206746038

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Akt2 Monoclonal Antibody, 100ul Recombinant Ab Production Acts as a GTPase activitorThis gene is a putative oncogene encoding a protein belonging to a subfamily of serine threonine kinases containing SH2 like (Src homology 2 like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of

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Description

Acts as a GTPase activitor in vitro for CDC42 and RAC1

Defects in this gene result in premature ovarian failure type 5

The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition

Cofilin 1 encoded by CFL1 can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner

The encoded protein may play a role in spermatogenesis

Akt2 Monoclonal Antibody, 100ul Recombinant Ab Production Acts as a GTPase activitorThis gene is a putative oncogene encoding a protein belonging to a subfamily of serine threonine kinases containing SH2 like (Src homology 2 like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of

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